This procedure uses tissue engineering principles to facilitate the continued growth and development of the pulp-dentin complex. If the tooth has an immature apex and necrotic pulp, regenerative endodontics allows for continued root development, thicker dentin walls, longer root length, and a closed apex, thus reducing the risk of fracture during tooth function.
Success is dependent on the activity of stem cells from the apical papilla (SCAP). These stem cells have enormous potential for tissue regeneration and bioroot engineering.
All immature teeth with open apices may be considered candidates for regenerative treatment, even if they have obvious pulp-space infection or a discharging sinus tract.